Fitoterápicos em Síndrome de Tourette

A procura por tratamentos ditos "naturais" para as diversas doenças é muito comum. Coloco naturais entre aspas pois mesmo as substâncias naturais das plantas são compostos químicos e agem da mesma forma nos receptores do nosso organismo. A diferença entre os fitoterápicos e os medicamentos ditos alopáticos é que os segundos são sintetizados em laboratório. Mas, no fundo, são medicamentos do mesmo modo, com efeitos colaterais, variados graus de eficácia e muitas vezes tão caros quanto os alopáticos. Assim, a escolha pelos fitoterápicos, em geral,  tem mais a ver com uma escolha filosófica do paciente do que com uma verdadeira indicação médica.
O artigo a seguir (coloco o resumo), avaliou dois fitoterápicos da medicina chinesa para a ST.

Chin Med. 2014 Feb 7;9(1):6. doi: 10.1186/1749-8546-9-6.

Herbal medicines for treating tic disorders: a systematic review of randomised controlled trials.

Kim YH, Son CG, Ku BC, Lee HW, Lim HS, Lee MS1.

Author information

Abstract

BACKGROUND:

It was reported that 64% of tic disorder patients used complementary and alternative medicine. This review aims to evaluate the efficacy of herbal medicines in treating tic disorders.

METHODS:

We searched eight databases including MEDLINE and CINAHL from their respective inceptions up to September 2013. The search terms were related to the concept of "herbal medicine" AND "tic disorder OR Tourette's syndrome". We included randomised controlled trials (RCTs) of any type of herbal medicines. We assessed the methodological quality of the trials according to the Cochrane risk of bias criteria.

RESULTS:

Sixty one studies were identified, and four RCTs met the inclusion criteria. Two types of herbal medicines, Qufeng Zhidong Recipe (QZR) decoction and Ningdong (ND) granules, were used in the included RCTs. All four RCTs had a high risk of bias. Two RCTs tested the effects of QZR on the Yale Global Tic Severity Scale (YGTSS) score and response rate compared with conventional medicine. The meta-analysis showed significant effects of QZR on the YGTSS score with high statistical heterogeneity (n = 142; weighted mean difference: -18.34; 95% confidence interval (CI): -23.07 to -13.60; I2 = 97%) and the response rate (n = 142; risk ratio: 1.69; 95% CI: 1.39 to 2.06; I2 = 0%). One RCT compared ND granules with placebo and showed significant effects on the YGTSS score and response rate. The other RCT show significant effects of ND granules plus conventional medicine on the response rate compared with conventional medicine only.

CONCLUSION:

This systematic review provided first piece of limited meta-analytic evidence for the effectiveness of herbal medicines in improving the symptoms of tic disorders.

PMID:

 

24507013

 

[PubMed] 

PMCID:

 

PMC3930107

 

Free PMC Article